To quantify deformation from continuous experimental biomedical imaging of specimens, we developed a digital volume correlation software, Your DVC. This open-source software can measure the deformation of a series of biomedical images (more than two) of a specimen, with control over interpolation order, regularization type and coefficient, and the initial field guess, enabling accurate voxel-level displacement and strain analysis.
Using our software on continuous imaging data, we successfully track the experimental deformation of specimens, ranging from cellular to tissue level depending on the imaging resolution. The measured deformation can be analyzed directly or incorporated into corresponding computational models as boundary conditions or field inputs, bridging experimental observations with predictive simulations.
